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Metformin (Glucophage) and Conception

Metformin or Glucophage is an oral medication that is used for treating diabetes of type 2 and resistance of insulin in the polycystic ovarian syndrome, abbreviated as PCOS. There are few other names for this oral medication which include Diformin, Glucophage and Glumetzaand Glycon. As Wikipedia says Metformin is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function.

Glucophage and pregnancy

Many pregnant woman look answer for “Is it safe to consume glucophage during pregnancy?”. Well! Before your pregnancy and in your pregnancy period, the level of your blood sugar should be normal and under control in order to stop the chance of increased risks of defects in your future baby and some other complications. Insulin is normally your choice for medication because it can easily manage the blood sugar levels as compared to oral medication. However, Metformin is also very helpful to treat diabetes type II in women who are pregnant, especially when insulin is not enough and gives only half control over blood sugar levels.

If you are planning to become pregnant, you should take advice from your doctor before pregnancy to examine that which medication you should take and which is not appropriate for you. If you become pregnant and you use Metformin during your pregnancy then it is not good idea to stop yourself from taking medication. Before making any decision, you should consult your doctor, as he can only tell you if you should continue with your medication. Studies showed that women having polycystic ovarian syndrome (PCOS) who are getting their treatment with Metformin, they have higher chances to get pregnant. Pregnant women who do not stop taking Metformin in their first trimester, they may get little risk of miscarriage.

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Some studies also showed that taking Metformin in complete duration of your pregnancy may also decrease the development of the gestational diabetes. According to your previous medical history, your doctor will determine your health condition and he will suggest you to continue Metformin throughout your pregnancy or stop it when to make your pregnancy safe. It is good idea if you discuss about this issue with your doctor before you become pregnant.

Is Metformin can affect unborn baby during pregnancy

Some studies showed a relationship between the usage of Metformin in your pregnancy and preeclampsia while other studies compared Metformin use with the insulin in your pregnancy. It found that it is not Metformin that can increase the chances of increased complications for both mothers and babies. In babies, high levels of bilirubin, also called jaundice exposed to the Glucophage in pregnancy period. All these reports do not predict that Metformin is the reason behind jaundice.

Metformin dosage

To treat diabetes type II in adults, Metformin or Glucophage is normally started at 500 mg dose two times in a day or 850 mg once in a day. The dose is then increased to 500 mg for week and 850 mg after two weeks. It depends on how much quantity of Metformin you can easily bear. It also based on the response of glucose levels in your blood. If you want to take the maximum dose then you can take dose of 2550 mg daily but in three times. If you use extended tablets then you can start Metformin dosage of 500 mg or 1000 mg every day with your lunch. You can increase dose to maximum 2000 mg once or by dividing in two doses. Glumetza tablets should be taken once in a day. It is recommended to take Metformin always with meals. If patient is 10 to 16 years old then starting dose should be 500 mg two times in a day.

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Glucophage overdose

Some people ask “Is there any problem in taking overdose of Glucophage?”. Along with other medicines, it is also possible to take a lot of Metformin. Affects of taking overdose of Metformin differ depending on various factors such as how much you take Metformin dose in once day or whether you are taking some other medicines, drugs or drinking alcohol along with it.

Symptoms of Metformin overdose

If you take Metformin overdose, you may get risks of hypoglycemia or low blood sugar and lactic acidosis.

  • If patients experience low blood sugar then possible symptoms they can face include: Shakiness, Sweating, Dizziness, Extreme hunger, Blurry vision and Cold sweats. Severe symptoms of low blood sugar are: Confusion, Coma, Loss of coordination, Loss of life, difficulty in speaking and Seizures.
  • Symptoms of lactic acidosis include: Pain of muscles, breathing problems, feeling cold all time, feeling weak and tired, dizziness, irregular heartbeat and even loss of life.


Glucophage side effects

Side effects experienced by most people experience are vomiting, bloating, gas, diarrhea and appetite loss and nausea. All these glucophage side effects occur in one patient from three. There may be some side effects that cause therapy to discontinue it. These side effects occur due to medication and it can be reduced by decreasing dose of medication.

Delores C. West is a compassionate healthcare professional with a focus on women's health and wellness. As a certified nurse-midwife, Delores is dedicated to providing comprehensive care to women throughout their reproductive journey. With a warm and nurturing approach, she empowers her patients to make informed decisions about their health and well-being. Delores's expertise in women's health makes her a trusted resource for individuals seeking personalized and compassionate care. Connect with her on LinkedIn to learn more about her commitment to women's health and wellness.